Lipid-altering agents encompass several classes of drugs that include hydroxymethylglutaryl (HMG) CoA reductase inhibitors or statins, fibric acid derivatives, …
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Statins are a group of medications that treat high cholesterol levels. Names of statins include atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor). There isn't one best statin to take. No individual statin has been proven to be best at preventing heart attacks and strokes. But there is evidence that rosuvastatin and ...
Based on the long-term benefits calculations by Pencina and colleagues, 9 high-intensity statin use could prevent 51% to 71% of premature ASCVD events among patients age 30 to 39 years when …
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The most commonly reported side effects of statins include: A headache. belching or excessive gas. constipation. croaky voice or hoarseness. difficulty sleeping. heartburn, indigestion, nausea, or stomach discomfort. lower back or side pain, tenderness around the eyes or cheekbones.
A CAC score of 1 to 99 suggests statin therapy, particularly for patients 55 years and older. If the CAC score is 100 or greater or in the 75th percentile or greater, statin therapy is indicated ...
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The anti-inflammatory effects of statins may be beneficial in the area of thyroid eye disease. A recent report shows that oral statins may have the potential to decrease the conversion of Graves' disease to thyroid-associated orbitopathy by 40%. 10,11 A 2018 study of 30 patients shows that statin users tend to have a reduced number of …
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Commentary based on: van Rosendael AR, van den Hoogen IJ, Gianni U, et al. Association of statin treatment with progression of coronary atherosclerotic plaque composition.JAMA Cardiol 2021;6:1257-66. Introduction. Coronary artery disease (CAD) is highly prevalent and if inadequately treated can often lead to major adverse …
If you take one, you can expect your LDL cholesterol to drop by anywhere from 35% to 50% or more, depending on the type of statin you take and your dose, Nissen says. And that could cut your ...
High-dose therapy (greater than one-half the maximal recommended dosage) Impaired liver/renal function (creatinine clearance < 30 mL per minute per 1.73 m 2 [0.50 mL per second per m 2 ]) Low body ...
The most commonly reported side effects of statins include: A headache. belching or excessive gas. constipation. croaky voice or hoarseness. difficulty sleeping. …
Rhabdomyolysis can cause extreme muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low. Only a few cases of rhabdomyolysis occur per million people taking statins. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins.
Steven Novella on January 26, 2011. Tweet. A recent Cochrane review of the use of cholesterol-lowering statin drugs in primary prevention has sparked some controversy. The controversy is not so much over what the data says, but in what conclusions to draw from the data. Statin drugs have been surrounded by controversy …
Based on moderate-quality evidence from RCTs, maximally tolerated statin therapy is recommended for patients 20 to 75 years of age with an LDL-C level of 190 …
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Not everyone who takes a statin will have side effects, but some people may be at a greater risk. Risk factors include: 1. Taking multiple medicines to lower your cholesterol. 2. Taking …
Key takeaways: Statins are a group of medications that treat high cholesterol levels. Names of statins include atorvastatin (Lipitor), rosuvastatin (Crestor), and …
Manufacturer. Statin 10mg Tablet is used in the treatment of High cholesterol,Prevention of heart attack and stroke. View Statin 10mg Tablet (strip of 10 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.
Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force [Internet]. Show details. Contents; …
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Statins are drugs that can lower your cholesterol. They work by blocking a substance your body needs to make cholesterol. Lowering cholesterol isn't the only …
With respect to the prevalence of statin use in older adults, another analysis from the Patient and Provider Assessment of Lipid Management (PALM) registry 7 compared statin use and dosing between adults >75 and ≤75 years old in the setting of either primary or secondary prevention. Approximately 25% (1,704) of the 6,717 …
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References. Collins R, Reith C, Emberson J, et al. Interpretation of the evidence for the efficacy and safety of statin therapy. Lancet 2016;388:2532-61.; Koskinas KC, Siontis GCM, Piccolo R, et al. Effect of statins and non-statin LDL-lowering medications on cardiovascular outcomes in secondary prevention: a meta-analysis of randomized trials.
Statins (also called HMG-CoA reductase inhibitors) block an enzyme called HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A reductase) that is involved …